The right of the people to be secure in their persons, houses, papers, and effects, against unreasonable searches and seizures, shall not be violated, and no Warrants shall issue, but upon probable cause, supported by Oath or affirmation, and particularly describing the place to be searched, and the persons or things to be seized. (Source)
Every Crime shows favorite Amendment. This Amendment is why cops have to get warrants. Otherwise they are unlawfully seizing private property. Debate ranges on how specific warrents need to get.
This amendment protects you from having your home invaded and “evidence” taken or being arrested without due cause. This does not protect you from having to cooperate when the police come with a warrant for your computer. It also doesn’t protect you from being arrested when there is reasonable cause to think you are involved with a crime. Or when you commit a crime in their presence.
State and local governments may have looser/stricter regulations on what is required to get a warrant or what they can take as evidence when they do have one.
This amendment is probably one of the more known and discussed from the bill of rights.